Risk Of Coronary Artery Disease Associated With Familial Hypercholesterolemia Genetic Variants Is Independent Of Historical Low-Density Lipoprotein Cholesterol Exposure

Shoa L. Clarke,Catherine Tcheandjieu,Austin Hilliard,Kyung Min Lee,Julie Lynch,Kyong-Mi Chang,Donald Miller,Christopher J. O'Donnell,Philip S. Tsao,Daniel J. Rader,Peter Wilson,Yan V. Sun,Michael Gaziano,Themistocles L. Assimes

Circulation（2020）

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摘要

Introduction: Familial Hypercholesterolemia (FH) variants confer risk for coronary artery disease (CAD) even after adjusting for a single baseline LDL measure. Hypothesis: We hypothesized that a mo...

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