Effects of propofol, alfaxalone and isoflurane on cerebral blood flow and cerebrovascular reactivity to CO2 in dogs

G. Bini, K. Bailey, J. Voyvodic,L. Chiavaccini,K. Munana, E. Keenihan

Veterinary Anaesthesia and Analgesia（2020）

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摘要

Introduction: Propofol total intravenous anesthesia reduces cerebral blood flow (CBF) while maintaining cerebrovascular reactivity (CVR) to carbon dioxide (CO2). This is desirable when intracranial pressure is increased. We hypothesized that alfaxalone would behave similarly to propofol, while isoflurane would increase CBF and decrease CVR-CO2.

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关键词

cerebrovascular reactivity,propofol,cerebral blood flow,co2,isoflurane

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