Novel Target Genes And Epigenetic Pathways Involved In High Risk Acute Lymphoblastic Leukemia

Sara Deola,Dhanya Kizhakayil,Sheanna M Herrera,Muhammad Elnaggar,Che-Ann Lachica,Giusy Gentilcore,Ayman Saleh,Anila Ejaz,Zehra Fadoo,Kulsoom Ghias,Irene Pusceddu,Irene M Cavattoni,Ramzi Temanni,Najeeb A Syed,Fazulur R Vempalli,Patrizia Comoli,Tommaso Mina,Chiara Cugno

BLOOD（2020）

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摘要

Acute leukemias (AL) is a major cause of cancer death in young age. Extensive research is being conducted to identify novel and innovative approaches for leukemia treatment. Transcriptomic and epigenetic studies might help to discover potential targets, paving the way for molecular-targeted therapies.

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