MICROWAVE-ASSISTED ECO-FRIENDLY SYNTHESIS AND ANTIMICROBIAL EVALUATION OF HETEROAROMATICALKENE HYDROXAMIC ACID.

Journal of emerging technologies and innovative research(2019)

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摘要
All over the world due to the highly growing awareness over worldwide environmental pollution and environmental legislation, recent years have witnessed a phenomenal highly growth in the application of microwave irradiation in area of hetero aromatic organic chemistry synthesis and its large applications. Heterocyclic compounds are abundant in nature and are of great significance value to the human life because their structural subunits exist in many natural products in nature as vitamins, hormones, and antibiotics proteins. They have highly attracted considerable attention in the design of biologically active Molecules and advanced in different area of organic chemistry. The various application of molecular diversity technique to the area of medicine discovery is a multidisciplinary effort in organic synthesis with all over the world.. Medicinal chemistry concerns with the discovery, development, interpretation and the identification of mechanism of action of biologically active compounds at the molecular level in specific area. Encouraged by the above reports and on the basis of our research programmed for development of eco-friendly synthetic protocol for biologically active compounds as well as in pursuing of our work on new solvent-free crystals here we report the synthesis of Heteroaromaticalkene Hydroxamicacid. In case of one-port of aromatic organic compounds using AlCl3 as a catalyst under microwave irradiation and in solvent-free condition gave Heteroaromaticalkene Hydroxamicacid with improved yield is described amounts.
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