New 30-substituted derivatives of pentacyclic triterpenes: preparation, biological activity, and molecular docking study

Elwira Chrobak,Ewa Bębenek,Krzysztof Marciniec,Monika Kadela-Tomanek,Szymon Siudak,Małgorzata Latocha,Stanisław Boryczka

Journal of Molecular Structure（2021）

引用 5|浏览17

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摘要

•A series of new 30-substituted triterpenes were synthesized.•Triterpenes were evaluated for their anticancer activities.•The ADME parameters of the synthesized triterpenes were analyzed.•The molecular docking studies of all compound were predicted.

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关键词

Natural compounds,Triterpenes,Antiproliferative activity,Molecular docking

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