Extract of pre-germinated brown rice protects against cardiovascular dysfunction by reducing levels of inflammation and free radicals in a rat model of type II diabetes

•An extract of PGBR (EP) has high levels of γ-oryzanol, flavonoids, and anthocyanidin.•It can improve insulin activity, glycolysis, glycogenesis, lipid synthesis, and lipid absorption.•This study is the first to report that EP protects against cardiovascular complications associated with T2DM.