P10. Bone morphogenetic protein usage decreases the risk of reoperations after anterior cervical discectomy and fusion: a five-year survivorship analysis

BACKGROUND CONTEXT Surgical intervention of the cervical spine is a challenging procedure that can present postoperative complications such as dysphagia, swelling, and reoperations. However, the risk of reoperation can possibly be mitigated with the use of biologics to enhance fusion. There is paucity in the literature on long-term incidence of reoperations after application of BMP during ACDF. PURPOSE To evaluate if bone morphogenetic protein usage during anterior cervical discectomy and fusion will decrease reoperation rates. STUDY DESIGN/SETTING Retrospective review of the PearlDiver database between 2006-2014. PATIENT SAMPLE Matched cohort of 35,544 ACDF patients. OUTCOME MEASURES Reoperations. METHODS Patients undergoing an anterior cervical discectomy and fusion between the years 2006-2014 were isolated in the PearlDiver database. Patients receiving BMP operatively and a control with no BMP were matched for baseline demographics including age, sex, and comorbidities. A Kaplan Meier Survival analysis assessed five-Year Reoperation-Free Survival between BMP patients and controls. Statistical significance was set to p RESULTS A matched cohort of 35,544 ACDF patients was isolated. A total of 17,772 patients received BMP while undergoing cervical fusion and 17,772 did not receive any BMP during surgery. Patients did not differ in age, sex or comorbidities (p\u003e0.05). Kaplan Meier survival analysis showed patients receiving BMP during cervical fusion were significantly more likely to remain reoperation free five years after index surgery (p CONCLUSIONS For patients receiving bone morphogenetic protein during anterior cervical discectomy and fusion, Kaplan-Meier survival analysis following five years post index surgery had showed a 91.3% reoperation-free survivorship. FDA DEVICE/DRUG STATUS This abstract does not discuss or include any applicable devices or drugs.