Synthesis and Characterization of Tris(nicotinohydroxamato) Vanadium(III) Complex

The tris(nicotinohydroxamato) vanadium(III) complex of composition [V(C5H4NCONHO)3] have been synthesized by the reaction of VCl3 with three equivalents of potassium salts of nicotinohydroxamate in methanol medium under nitrogen atmosphere. The characterization of complex has been accomplished by elemental analyses, molar conductivity, magnetic moment measurements, IR, electronic and mass spectral studies. An octahedral geometry around vanadium, inferred from physicochemical and spectral studies has been proposed for complex. The antimicrobial activities of the newly synthesized complex, ligand and precursor VCl3 have been evaluated against some pathogenic bacteria as E.coli, S.aureus, S.typhi, S. paratyphi, S.epidermidis and K.pneumoniae and fungi such as A.niger, B.fulva and M.circinelloid by minimum inhibitory concentration method. The complex exhibited promising antimicrobial activity relative to free ligand and metal precursor.