A Rare Case of Hemorrhagic Melanotic Schwannoma in a 38-year-old Female.

Rakesh Danny Biju, Maria Duignan,Monish Maharaj,Fouzia Ziad,Zakier Hussain

Asian journal of neurosurgery(2020)

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摘要
Melanotic schwannoma is a rare form of nerve sheath tumor composed of melanin-producing neoplastic Schwann cells. Less than 200 cases have been reported worldwide. The entity has been associated with Carney complex, a rare genetic disorder characterized by multiple benign tumors. A 38-year-old female presented to our unit with sudden-onset lower back pain and radiculopathy triggered by a mechanical injury. Imaging demonstrated a lesion within the left L5/S1 neural exit foramen with remodeling of bony architecture typical of a chronic, benign process. She proceeded for resection and histology revealed a psammomatous melanotic schwannoma. The patient recovered well with improvement in symptomology. Due to the aggressive nature of the disease, she remains under surveillance for local recurrence and distant metastasis. Clinicians should be aware of this malignant entity, despite its possible presentation with radiological features of a chronic, benign process. Unusual characteristics such as hemorrhage should be treated with a high index of suspicion.
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关键词
Carney complex,melanotic schwannoma,nerve sheath tumor,psammoma bodies
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