The Photothermal And Adsorption Properties Of Different Surfactant-Modified Caesium Tungsten Bronze

Cesium tungsten bronze nanoparticles have excellent near infrared lightresponse characteristics, easy surface modification and low cytotoxicity, which are attractive for tumor photothermal therapy. In this paper, cesium tungsten bronze nanoparticles were synthesized by a simple hydrothermal reaction method using cesium hydroxide as raw material. In order to improve the properties of dispersion and drug loading, the modification of two different surfactants was investigated. Themorphology of cesium tungsten bronze nanoparticles modified with polyvinylpyrrolidone had no significant change in scanning electron microscope, but it had high photothermal properties, with a photothermal conversion efficiency of 23.1%. The drug loading capacity of CTAB-Cs0.32WO3 is 47.9 mg/mL accordingly. The michigan cancer foundation-7 (MCF-7) cell activity was only 27.33% when the concentration of CTAB-Cs0.32WO3-DOX was 1mg/ml under irradiation of 980nm. These results showed that cesium tungsten bronze nanoparticles surface modified with hexadecyltrimethyl ammonium bromide (CTAB) had excellent anti-tumor ability.