Safety of lumbar puncture procedure in an international research setting during acute HIV infection.

Phillip Chan,Joanna Hellmuth,Donn Colby,Eugene Kroon,Carlo Sacdalan,James Fletcher,Payal Patel, Suteera Pinyakorn,Victor Valcour,Jintanat Ananworanich,Serena Spudich

Journal of Virus Eradication（2018）

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摘要

Background: Cerebrospinal fluid (CSF) sampling at the time of acute HIV infection (AHI) is crucial in understanding NeuroAIDS pathogenesis. Here, we report on the safety of performing a lumbar puncture (LP) during untreated AHI and follow-up after initiation of combination antiretroviral therapy (cART).

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关键词

Lumbar puncture headache, acute HIV infection, cerebrospinal fluid, atraumatic spinal needle, RV254

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