Surface plasmon resonance biosensor for the detection of tau-amyloid beta complex

Tomas Springer,Erika Hemmerova, Giusy Finocchiaro,Zdenka Kristofikova,Martin Vyhnalek,Jiri Homola

Sensors and Actuators B: Chemical（2020）

引用 27|浏览1

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摘要

•New biosensor for the prospective AD biomarker - the complex of protein tau and Aβ.•The method enables the detection of the tau-Aβ complex in CSF down to sub-pM levels.•First reported sensor-based measurement of the levels of tau-Aβ complex in CSF samples.

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关键词

Alzheimer’s disease,Surface plasmon resonance (SPR) biosensor,Biomarker complex of protein tau and amyloid β,Gold nanoparticles,Detection

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