Cost-effectiveness of managing low-risk pulmonary embolism patients without hospitalization. The low-risk pulmonary embolism prospective management study

•Venous thromboembolism (VTE) is a common and sometimes morbid condition.•Typical inpatient care of VTE with hospital observation is expensive, ~$8.7 K/visit.•ED observation of low-risk PE has lower initial encounter costs than hospital observation.•ED observation of low-risk PE has shorter length-of-stay than hospital observation.