Immune characteristics of renal allograft donors with mesangial IgA deposition

International Immunopharmacology(2021)

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摘要
•Our data showed that 26% blood-related donors had mesangial IgA deposition.•IgA deposited in healthy donors contains galactose-deficient IgA1.•Levels of serum IgG anti-glycan antibodies in donors with IgA deposition were between healthy control and patients with IgAN.
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关键词
Immunoglobulin A nephropathy (IgAN),Donor,Latent mesangial IgA deposition,Zero-hour renal biopsy,Galactose-deficient IgA1 (Gd-IgA1)
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