Tp53 And Pten As Driver Mutations In Zenker'S Carcinoma-A Clinical Presentation

Zsanett Noel,Sylvia Hoeller,Michel Bihl,Laurent Muller

CLINICAL CASE REPORTS（2020）

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摘要

Zenker carcinoma is still being treated empirically because of the lack of evidence- based guidelines. We report for the first time about the genetic examination of this rare entity. The revealed mutations show genetic similarities with HPV(-)HNSCC which suggests that well-known therapeutic strategies may be applicable for this disease

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关键词

carcinoma,mutation,PTEN,TP 53,Zenker

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