Investigating the Effects of the Core Nitrogen Atom Configuration on the Thermodynamic Solubility of 6,5-Bicyclic Heterocycles.
Bioorganic & Medicinal Chemistry Letters(2020)
Key words
ChromlogD(7.4),Fasted State Simulated Intestinal fluid (FaSSIF),General Solubility Equation (GSE),Kinetic solubility,Physicochemical properties,Simulated lung fluid (SLF),Thermodynamic solubility
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