RIP3-mediated necroptosis was essential for spiral ganglion neuron damage

Xi Wang,Xiaobo Mao,Kun Liang,Xiaodong Chen,Bo Yue,Yang Yang

Neuroscience Letters（2021）

引用 6|浏览5

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摘要

•RIP3 and pRIP3 were upregulated with SGNs injury promoted.•RIP3 overexpression promoted while knockdown inhibited ouabain-induced necroptosis.•RIP3 knockdown reduced the phosphorylation of MLKL, but not affected MLKL.

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关键词

RIP3,Spiral ganglion neuron,Necroptosis,Hearing loss

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