Bioactive properties of chitosan stabilized magnetic nanoparticles – Focus on hyperthermic and anti-amyloid activities

Journal of Magnetism and Magnetic Materials(2020)

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摘要
•The chitosan coated magnetic nanoparticles in the presence of urea were prepared.•TEM, TGA, UV/VIS and 13C NMR were used to prove the chitosan coating of MNPs.•The chitosan layer influences on the heating efficiency of MNPs in hyperthermia.•Chit-MNPs destroy a-lactalbumin amyloid fibrils in concentration-dependent manner.
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关键词
Iron oxide nanoparticles,Chitosan,Magnetic hyperthermia,α-Lactalbumin amyloid fibrils
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