RIFM fragrance ingredient safety assessment, benzene, 1,3,5-trimethoxy-, CAS Registry Number 621-23-8

A M Api,D Belsito, S Biserta, D Botelho, M Bruze,G A Burton,J Buschmann,M A Cancellieri,M L Dagli, M Date,W Dekant,C Deodhar,A D Fryer,S Gadhia,L Jones,K Joshi,M Kumar,A Lapczynski,M Lavelle, I Lee,D C Liebler,H Moustakas,M Na, T M Penning, G Ritacco, J Romine,N Sadekar,T W Schultz,D Selechnik,F Siddiqi,I G Sipes,G Sullivan, Y Thakkar,Y Tokura

Food and Chemical Toxicology（2021）

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摘要

•Benzene, 1,3,5-trimethoxy-; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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关键词

Genotoxicity,Repeated dose,Developmental,And reproductive toxicity,Skin sensitization,Phototoxicity/photoallergenicity,Local respiratory toxicity,Environmental safety

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