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Development of a Large-Scale Route to Glecaprevir: Synthesis of the Macrocycle Via Intramolecular Etherification

Jeffrey M. Kallemeyn,Kenneth M. Engstrom,Matthew J. Pelc,Kirill A. Lukin,Westin H. Morrill, Haojuan Wei,Timothy B. Towne,Jeremy Henle,Nandkishor K. Nere,Dennie S. Welch,Shashank Shekhar,Matthew M. Ravn,Gang Zhao,Michael G. Fickes,Chen Ding,John C. Vinci, James Marren,Russell D. Cink

Organic Process Research & Development（2020）

引用 10|浏览2
关键词
glecaprevir,ABT-493,HCV,intramolecular etherification,macrocycle
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