Molecular self-assembly-inspired attosecond nanomedicine crystal nanobiophotonic approach: challenges and opportunities

Molecular self-assembly, a part of bottom-up self-assembly approach, inspires the construction of challenging molecular topologies. Advances in attosecond sciences lead a wealth of important discoveries in biochemical molecular ultrafast dynamic processes relevant to a single atomic, molecular etc. quantum state toward the generation and application of extreme-ultraviolet (EUV) sub-femtosecond approaches, which offer opportunities to probe challenging molecular topologies. Measurement and control of space-time biophoton-bioelectron coupling dynamic motion in complex biochemical molecular structures-inspired heterosingle quantum state systems are a formidable challenge. Different from infrared van der Waals nanostructures and Borromean rings with three macrocycle interlocked architectures, blue-shift complex structure nanomedicine crystals containing heterosingle molecules, heterosingle atoms, single biophotons, single bioelectrons relied up a directed design according to at least four factor or more factor orthogonal mathematics statistics coupling a bottom-up self-assembly approach wherein inter-molecular self-assembly and intra-molecular self-assembly relied up short range forces like hydrogen bonding, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interaction, electrostatic interaction, folding mechanisms and long range forces like electromagnetic interactions were involved. By application of self-assembled nanomedicine crystals and self-assembled sub-femtosecond EUV laser micro-photoluminescence (PL) spectroscopy system with third harmonic generator etc. tools, time-resolution blue-shifted laser micro-PL spectroscopy from the near infrared to the ultraviolet was detected and revealed by a sphere integrator. It is concluded that molecular self-assembly-inspired nanomedicine crystal as a testing model paves a way toward facilitating attosecond nanobiophotonic approaches at the single molecular level that is below the diffraction limit of light, which facilitates state-of-the art transformational and translational technologies.