Diversity in Androgen Receptor Action Among Treatment-naïve Prostate Cancers Is Reflected in Treatment Response Predictions and Molecular Subtypes

Salma Ben-Salem,Qiang Hu,Yang Liu,Mohammed Alshalalfa,Xin Zhao, Irene Wang,Varadha Balaji Venkadakrishnan,Dhirodatta Senapati,Sangeeta Kumari,Deli Liu,Andrea Sboner,Christopher E Barbieri,Felix Feng,Jean-Noel Billaud,Elai Davicioni,Song Liu,Hannelore V Heemers

European Urology Open Science（2020）

引用 6|浏览26

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摘要

Treatment options for metastatic prostate cancer are increasing without information needed to choose the right treatment for the right patient. We found variation in the behavior of the target for the default first-line therapy before treatment, which may help optimize treatment plans.

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关键词

Disease stratification,Treatment response,Hormonal therapy,Chemotherapy,Radiotherapy,Biomarker,Castration

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