Disruption of rat deep cerebellar perineuronal net alters eyeblink conditioning and neuronal electrophysiology

Deidre E O'Dell,Bernard G Schreurs,Carrie Smith-Bell,Desheng Wang

Neurobiology of Learning and Memory（2021）

引用 3|浏览13

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摘要

•PNN in rat DCN shows developmental changes.•Application of ChABC in vivo and in vitro can digest PNN in rat DCN.•In vivo degradation of the PNN in the rat DCN has effects on EBC.•Vehicle rats have sex differences in EBC not present in the ChABC-infused animals.•PNN degradation alters membrane properties of rat DCN neurons.

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关键词

PNN,DCN,Electrophysiology,Eyeblink conditioning,ChABC

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