Genome-wide Association Study of Postoperative Cognitive Dysfunction in Older Surgical Patients.

Marc Rickenbacher,Céline S Reinbold,Stefan Herms,Per Hoffmann,Sven Cichon,Alexandra S Wueest,Andreas U Monsch,Luzius A Steiner,Nicolai Goettel

JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY（2022）

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摘要

In this patient cohort, a GWAS did not reveal an association between specific genetic alleles and POCD at 1 week and 3 months after surgery. Future genetic analysis should focus on specific candidate genes for POCD.

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关键词

blood samples, genetic polymorphism, genetic risk, noncardiac surgery, older patients, postoperative cognitive dysfunction

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