Lamellar shape lead tungstate (PbWO4) nanostructures as synergistic catalyst for peroxidase mimetic activity

Tungstate based nanomaterials have emerged as important class in transition metal oxide. In this study, Lead tungstate (PbWO4) nanostructures with lamellar morphology were prepared by hydrothermal method. The synthesized materials were characterized by XRD, SEM, FTIR, DLS, BET and PL. Nitrogen adsorption-desorption measurements indicated that the surface area of the synthesized lamellar morphology was similar to 86.225 m(2) g(-1). The lamellar-like morphology showed enhanced peroxidase-like activity owing to the large surface area, higher substrate interaction and efficient electron transportation. The results indicated higher reaction velocity (V-max = 13.56 x 10(-8) M s(-1)) and low Michaelis-Menten constant (km = 0.325 mM) value for nanostructures, providing evidence for higher affinity of novel structures towards the substrate and increased peroxidase-like activity. Finally, biocompatibility test was conducted by performing cytotoxicity experiments of PbWO4 nanostructures on MTT assays.