Therapeutic Potential of Angiotensin-Receptor-Neprilysin Inhibitors (ARNI) to Reduce Age-related Arterial Fibrosis and Stiffening

Isabel Schellinger,Angelika Dannert, Giriprakash Chodisetti,Karin Mattern, Joanna Jakubiczka-Smorag,Andreas Schuster,Gerd Hasenfuss,Uwe Raaz

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY（2019）

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Background: Arterial stiffness typically increases with age resulting in adverse hemodynamic conditions for a multitude of critical organs, such as heart, brain, and kidneys. As such, arterial stif...

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