Efficient reactions for the synthesis of pyrazolo[3,4‐b]pyridine and pyrano[2,3‐c]pyrazole derivatives from N‐methyl‐1‐(methylthio)‐2‐nitroethen‐1‐amine
Journal of Heterocyclic Chemistry(2020)
摘要
The efficient and novel method for the synthesis of pyrazolo[3,4‐b]pyridine and pyrano[2,3‐c]pyrazole derivatives from the multicomponent reaction of aromatic aldehydes (isatins), N‐methyl‐1‐(methylthio)‐2‐nitroethen‐1‐amine, and 3‐aminopyrazole or methyl 3‐hydroxy‐1H‐pyrazole‐5‐carboxylate under normal laboratory conditions was reported in this research. The advantages of this research are wide range of substrates, high yields, and simple operation.
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