Evaluation of Patients Who Followed By the Diagnosis of Mastitis in Oncology Hospital

Introduction: Mastitis is the general nomenclature of the inflammatory process in infectious and noninfectious breast tissue. Physical examination, culture, infection parameters, histopathology and radiological imaging are used in the diagnosis. The aim of this study is to obtain epidemiological data about mastitis and to provide a more rational approach to the treatment with evaluating the clinical and laboratory findings. Materials and Methods: Mastitis patients who were treated between 01 January 2006-01 January 2015 at Health Sciences University Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital were evaluated. Acute phase reactants, microbiological characteristics, clinical and laboratory data were evaluated retrospectively on day 0th, day 3rd, week 1st, week 2nd and week 3rd after infection. Our study was an observational epidemiological study and the results were evaluated with Mann-Whitney U test, Chi-square and Fisher's Exact test in IBM SPSS statistic program version 23.0. p<0.05 was considered significant in interpretation. Results: A total of 33 patients were included in our study, 4 of which were lactating, 29 of which non-lactating mastitis patients. Enterobacter cloacae, Escherichia coli, Pseudomonas aeruginosa were isolated in one sample, Candida albicans, methicilline resistant coagulase-negative staphylococcus, methicilline sensitive coagulase-negative staphylococcus, were isolated in two samples, and methicilline sensitive Staphylococcus aureus was isolated in three samples. Oral or parenteral antimicrobial treatment was applied as treatment. All of the patients had redness in the breast, sensitivity in 28, ulcerated lesion in 12, purulent discharge in 20, fever in 21, nipple traction in four, and axillary lymphadenopathy in four. The most common clinical finding for empirical antibiotherapy was nipple traction, and the best response was fever. Conclusion: Mastitis is frequently caused by gram-positive microorganisms and empirical treatment should be included in these factors. The most effective parameters in the treatment follow-up were fever, redness, sensitivity and C-reactive protein. It was concluded that the microorganism detected by the invasive procedures and the determination of the resistance status should contribute to the treatment in the patients who completed the treatment period of 2-3 weeks and who did not respond to the treatment at the end of this period.