INFLUENCE OF RESIDUAL DIURESIS ON CARDIAC BIOMARKER NTproBNP IN CHRONIC HEMODIALYSIS PATIENTS

High levels of cardiac biomarker N-terminal probrain type natriuretic peptide (NTproBNP) are present in hemodialyzed population and are associated with increased cardiovascular morbidity and mortality risks. Factors influencing the increase of NTproBNP and its significance in dialysis patients are still a matter of debate. We conducted a study on a cohort of 3 months-old chronic hemodialyzed patients in order to reveal the relationship between NTproBNP levels and residual diuresis, volume status, intradialysis ultrafiltration (UF), left ventricular ejection fraction (LVEF). Weekly, for 3-months, we measured for each patient the following parameters: NTproBNP levels, volemic status, UF rate and LVEF, before and after the first hemodialysis session in the week. The comparison between the three groups was discussed and analyzed. There was a significant inverse correlation between NTproBNP values and diuresis in all three studied groups, both before and after the dialysis sessions.