Deletion of miRNA-22 Induces Cardiac Hypertrophy in Females but Attenuates Obesogenic Diet-Mediated Metabolic Disorders.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2020）

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摘要

This study reveals that miRNA-22 deletion induces cardiac hypertrophy in females without affecting myocardial function. In addition, our findings suggest miRNA-22 as a potential therapeutic target to treat obesity-related metabolic disorders in females.

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关键词

Cardiac hypertrophy,Female,Metabolic dysfunction,Obesity,miRNA-22

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