Preparation of Balsa-Nanosilver Anti-infective Eco-friendly Dressing and Its Effect on Wound Healing

This study aimed to prepare an anti-infective Eco-friendly dressing of balsa-Nanosilver, which should have antibacterial activity in vitro and promote wound healing in vivo. The balsa-Nanosilver was prepared using delignification (group Control) and dopamine gule (group A) methods respectively, at 1mmol/L, 2mmol/L, 4mmol/L (Namely group B, C and D). Finally, The Balsa-Nanosilver was observed as Nanosilver spherical particles and bedding dopamine colloid. FTIR showed that the Nanosilver had been adhered and the contact angle test showed that the material was still very hydrophilic. In vitro antibacterial effect was significant on E. coli and S. aureus. The cytotoxicity of the balsa-Nanosilver dressing was not found until day 7. On day 7, the healing rates were 34.5%, 40.8%, 57.9%, 69.3% and 73.5% in Group Control, A, B, C and D, respectively. The wound healing rate was higher in the C and D groups than these in the other three groups (P < 0.05).