Glymphatic Cerebrospinal Fluid and Solute Transport Quantified by MRI and PET Imaging

•DCE-MRI is a robust imaging platform for quantifying glymphatic transport.•Glymphatic transport and CSF flow dynamics is dependent on body posture.•T1 mapping can quantify glymphatic transport and cervical lymph node drainage concurrently.•Glymphatic transport kinetics are heterogenous across brain regions.•Regularized optimal mass transport analysis incorporates advective as well as diffusion terms.•Glymphatic transport can be measured by positron emission tomography.