Cytomegalovirus-Specific Immunoglobulin G Is Associated With Chronic Lung Disease in Children and Adolescents from Sub-Saharan Africa Living With Perinatal Human Immunodeficiency Virus

Dan Hameiri Bowen,Evgeniya Sovershaeva,Bethany Charlton, Cecilie Schive,Jon Odland,Grace McHugh,Tsitsi Bandason,Justin Mayini,Rashida A Ferrand,Louis-Marie Yindom,Sarah L Rowland-Jones

CLINICAL INFECTIOUS DISEASES（2021）

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摘要

In a cross-sectional study of 296 children and adolescents from Zimbabwe living with perinatal human immunodeficiency virus, individuals with the top tertile of cytomegalovirus-specific immunoglobulin G titer had an increased odds of chronic lung disease (odds ratio, 3.33; 95% confidence interval, 1.37-8.85; P=.010).

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关键词

cytomegalovirus, HIV, immunoglobulin G, lung disease

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