Bridging the age gap in breast cancer. Impacts of omission of breast cancer surgery in older women with oestrogen receptor positive early breast cancer. A risk stratified analysis of survival outcomes and quality of life

European Journal of Cancer(2021)

引用 30|浏览48
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摘要
•Propensity matched study of women >70 with breast cancer comparing surgery or PET•Unmatched analysis found surgery improves overall & disease-specific survival.•Matched analysis (stage, age, health, frailty) found similar disease-specific survival•Surgery led to adverse events in 19% & negative impacts on QoL and physical function•Less fit women >85 may be offered PET to reduce morbidity, without survival detriment
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关键词
Adjuvant endocrine therapy,Breast cancer,Older women,Patient-centred outcomes,Primary endocrine therapy,Propensity score matching,Quality of life,Surgery,Survival
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