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Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.

Dillon H. Miles,Xuelei Yan,Rhiannon Thomas-Tran,Jeremy Fournier,Ehesan U. Sharif,Samuel L. Drew,Guillaume Mata,Kenneth Lawson,Elaine Ginn,Kent Wong,Divyank Soni,Puja Dhanota,Stefan G. Shaqfeh,Cesar Meleza,Ada Chen,Amber T. Pham,Timothy Park, Debbie Swinarski,Jesus Banuelos,Ulrike Schindler,Matthew J. Walters,Nigel P. Walker,Xiaoning Zhao,Stephen W. Young,Jie Chen,Lixia Jin,Manmohan Reddy Leleti,Jay P. Powers,Jenna L. Jeffrey

ACS Medicinal Chemistry Letters（2020）

Cited 16|Views36
Key words
PI3K gamma,inhibitor,selective,azaindole,immunomodulation,cancer
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