Kappa Opioid Receptor on Pulmonary Macrophages and Immune Function.

Si Zeng,Yinbo Zhong,Jie Xiao,Jiafu Ji,Jin Xi,Xinchuan Wei,Renyu Liu

Translational perioperative and pain medicine（2020）

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摘要

Our results indicate that KORs may play a critical role in the modulation of the pulmonary inflammatory process by their activation in macrophages. Selective KOR agonists exert their anti-inflammatory effects acutely on lung macrophages, within 1-2 hours of LPS-stimulated inflammation .

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关键词

Alveolar macrophages,Kappa opioid agonist,Lipopolysaccharide,Pulmonary inflammation,Salvinorin A,U50488

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