Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material.

PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES(2020)

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摘要
Extracts of nine plants were studied for DPPH radical scavenging and reducing abilities. Pentatropis spiralis, Calotropis procera, Helitropium curassavicum, Withania somnifera and Chenopodium album showed reducing power ranging from 34% to 146%. Suaeda fruticosa, Trianthema portulacastrum, Pluchea lanceolata and Rumex dentatus has excellent antioxidant potential proved by their DPPH scavenging and reducing power. 1000 mu g/10 mu l chloroform extract of S. fruticosa gave 92% scavenging with IC50 value less than 0.7 mu g/10 mu l while its hexane extract possessed 80% reducing activity at 100 mu g/10 mu l concentration. DPPH free radical scavenging by methanolic extract of Trianthema portulacastrum was 60% and 76% at 1000 and 100 mu g/10 mu l respectively with IC50 value of 0.03 mu g/10 mu l while the reducing activity of 124% at 100 mu g/10 mu l. Methanolic extract of P. lanceolata showed 91% and 70% scavenging activity at 1000 and 100 mu g/10 mu l with IC50 value of 0.7 mu g/ 10 mu l. Reducing power is comparable with the reference BHA standard that is 98% at 100 mu g/10 mu l concentration. Rumex dentatus' extracts are excellent DPPH scavengers and hydrogen donators produced 156% reduction. Chloroform extract was inefficient antioxidant. These results make these plants a candidate for future research for treating ailments due to imbalance in free radicals.
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Antioxidant activity,DPPH free radical scavenging,reducing power,wild plants
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