In-vivo analysis of iron-gold composite nanoparticles as potential exogenous contrast agents for Magnetomotive Optical Coherence Tomography (MMOCT)

Journal of Magnetism and Magnetic Materials(2020)

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摘要
•A new iron-gold (Fe-Au) composite magnetic nanoparticles (MNPs) were reported.•A new robust imaging method Magnetomotive Optical Coherence Tomography (MMOCT) was developed.•High contrast and specific background subtracted MMOCT images was generated.•The system was validated with in-vivo imaging of mice model.•A penetration dynamic of MNPs in tissue was also demonstrated.
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关键词
Magnetomotive optical coherence tomography,Contrast agents,Magnetic nanoparticles,Iron-gold composite,Nano-scale displacement,Frequency modulation
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