Collagens at the vertebrate neuromuscular junction, from structure to pathologies.

Neuroscience Letters（2020）

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摘要

•Collagens are the main constituants of extracellular matrix.•Among them, 6 are enriched at the neuromuscular junction.•Mice null for these collagens have been generated and present more or less severe defects of the neuromuscular junction.•So far, 2 of the 6 collagens have been shown to be causative in neuromuscular disorders.

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关键词

Collagens,Neuromuscular,Junction,Integrins,Perlecan,Congenital myasthenic syndromes,Myasthenia gravis

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