An Affective Neuroscience Model of Boosting Resilience in Adults.

•Taking an affective neuroscience approach, this paper introduces a simple three-route model of boosting resilience in adulthood.•This tripartite model is supported by a review of more than two-dozen behavioral and psychosocial strategies of boosting resilience.•The three general routes to resilience are 1) down-regulating the negative, 2) up-regulating the positive, and 3) transcending the self.•Some strategies, including social support and mindfulness, can boost resilience via more than one route.