Photocyclization of enamines to access Spiroindolines and Spirooxindoles in continuous flow

Tetrahedron Letters(2020)

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摘要
•A flow chemistry approach to the UV photocyclization of aryl-enamines to spiroindolines has been developed.•The substrate scope of the UV photocyclization of aryl-enamines to spiroindolines has been explored.•The utility of this flow methodology has been demonstrated in a shortened formal synthesis of (±)-horsfiline.•A novel UV mediated oxidative decarboxylation of an indoline-2-carboxylate is described.
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关键词
Photochemistry,Flow,Spiroindolines,Spirooxindoles
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