A Phase Ia/Ib, Dose-Escalation/Expansion Study Of Bi 907828 In Combination With Bi 754091 And Bi 754111 In Patients (Pts) With Advanced Solid Tumors.

Anthony W. Tolcher,Navid Hafez,Noboru Yamamoto,Jaehong Park,Rolf Grempler, Anthony G. Lucarelli,Mehdi Lahmar,Bushi Wang,Mrinal M. Gounder

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

TPS3660Background: Preclinical data show that the combination of a murine double minute 2–tumor protein 53 (MDM2–TP53) antagonist with anti-PD-1 and anti-LAG3 antibodies produces an anti-tumor effe...

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