Structural characterization, antibacterial activity and NorA efflux pump inhibition of flavonoid fisetinidol

Horlando Carlota da Silva,Antonio Linkoln Alves Borges Leal,Mauro Macedo de Oliveira,Humberto Medeiros Barreto,Henrique Douglas Melo Coutinho,Hélcio Silva dos Santos,Gilvandete Maria Pinheiro Santiago,Thiago Sampaio de Freitas,Igor Kleber Campos Lima,Alexandre Magno Rodrigues Teixeira,Carlos Emídio Sampaio Nogueira

South African Journal of Botany（2020）

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摘要

•Structural characterization by nuclear magnetic resonance and FT-IR of fisetinidol, a flavonoid isolated from B. pentandra stems.•Antibacterial and modulatory activities of fisetinidol against Escherichia coli and S. aureus.•Inhibition of the NorA efflux pump of S. aureus SA-1199B.

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关键词

Spectroscopy,Flavonoid,Antibacterial activity,Efflux pump,Staphylococcus aureus

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