Exploration of the relation between bronchial asthma and toil-like receptors

Chinese Journal of Asthma(2010)

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摘要
The bronchial asthma (asthma) is a chronic inflammatory airway disease characterized by celelular component and infiltration into the airway submucosa of cells, which contain eosinophils,labrocytes,lymphocytes, neutrophils and epitheliums. Asthma is result from the contribution of genetically susceptible individuals and the various environmental stimuli. Studies have examined the contribution of toll-like receptors (TLR) and immunocells to the development of asthma. Through identifying the various micro-organisms,TLR may be involved in mechanisms provoking Thl-or Th2-biased immune responses and may, therefore, be an important factor in either preventing or promoting asthma. This review will explore the relation between TLR and asthma,provide a new idea of therapeutic effect to asthma.\r\n\r\nKey words: \r\nToll like receptor ; Immunocell ; Bronchial asthma
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