Randomized Phase Ii Trial Of Topotecan Plus M6620 (Vx-970) Versus Topotecan Alone In Patients With Relapsed Small-Cell Neuroendocrine Cancers Including Small Cell Lung Cancer.

Nobuyuki Takahashi,Rasa Vilimas,Samantha Nichols,Linda Sciuto,Santhana Webb,Seth M. Steinberg,Yves Pommier,Anish Thomas

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

TPS3653Background: Ataxia telangiectasia and Rad3-related (ATR) is an essential kinase that senses stressed replication forks and orchestrates the multifaceted replication stress response. Cancer c...

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