Neurocognitive heterogeneity in 7-year-old children at familial high risk of schizophrenia or bipolar disorder: The Danish high risk and resilience study - VIA 7

Nicoline Hemager,Camilla Jerlang Christiani,Anne Amalie Elgaard Thorup,Katrine Søborg Spang,Ditte Ellersgaard,Birgitte Klee Burton,Maja Gregersen,Aja Neergaard Greve,Yunpeng Wang,Ron Nudel,Ole Mors,Kerstin Jessica Plessen,Merete Nordentoft,Jens Richardt Møllegaard Jepsen

Schizophrenia Bulletin（2022）

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摘要

•Neurocognitive heterogeneity exists in young bipolar offspring.•Neurocognitive heterogeneity exists in young schizophrenia offspring.•79.7% of young bipolar offspring display normal neurocognitive functions.•64.6% of young schizophrenia offspring display normal neurocognitive functions.•Neurocognitive heterogeneity relates to PGS, environment, functioning, and symptoms.

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关键词

Bipolar disorder,Schizophrenia,Familial high-risk,Neurocognition,Heterogeneity,Population-based cohort

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