Medically resistant juvenile myasthenia gravis following thymectomy: Role for FDG PET/CT

Thymectomy is part of a multimodal treatment strategy for juvenile myasthenia gravis. Symptoms that persist following thymectomy may be due to residual or ectopic thymic tissue. We report the use of FDG PET/CT to locate residual thymic tissue following thymectomy in a 10 year old girl with acetylcholine-receptor-antibody-positive myasthenia gravis, who remained refractory to medical therapy. The patient subsequently underwent completion thymectomy with improvement but not remission of her condition.