Antioxidant and anti-glycated TAT-modified platinum nanoclusters as eye drops for non-invasive and painless relief of diabetic cataract in rats
Chemical Engineering Journal(2020)
摘要
•Pt nanoclusters coated with TAT-conjugated dextran (DTPNCs) dispersed in 0.1%F127 (W/V) were developed.•DTPNCs exhibit antioxidant and anti-glycated activities.•DTPNCs demonstrate the significant effect of corneal permeation, excellent water solubility, safety and biocompatibility.•DTPNCs as eye drops for non-invasive and painless relief of diabetic cataract in rats.
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关键词
Antioxidant,Anti-glycation,Permeation,Eye drops,Diabetic cataract
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