AMPA receptor nanoscale dynamic organization and synaptic plasticities.

Current Opinion in Neurobiology(2020)

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摘要
•New imaging approaches have revealed the nanoscale organization of AMPA receptors.•AMPA receptors are partly organized in nanodomains facing glutamate release sites.•About half of AMPAR are not clustered and are mobile in synapses.•AMPA receptor surface diffusion regulates post-synaptic short-term plasticity.•AMPA receptor diffusion trapping at synapses participates to Long-Term Potentiation.
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