Structural Variant Of The Designer Peptide Manp: Differential Actions With Cgmp Activation In Cardiorenal Functions

Shinobu Sugihara,Tomoko Ichiki,Yang Chen,Gail J. Harty,Denise M. Heublein, Seethalakshimi R. Iyer,Brenda K. Huntley,S. J. Sangaralingham,Daniel J. Mccormick,Alessia Buglioni,John C. Burnett

Circulation（2017）

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摘要

Introduction: M-atrial natriuretic peptide (MANP) is a novel Mayo Clinic engineered guanylyl cyclase A (GC-A) receptor and 3’,5’-cyclic guanosine monophosphate (cGMP) activating peptide based on th...

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关键词

Natriuretic peptides, atrial, Cardiovascular therapeutics

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